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Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
The Gram-negative bacterial cell wall component lipopolysaccharide (LPS) is recognized by the noncanonical inflammasome protein caspase-11 in the cytosol of infected host cells and thereby prompts an inflammatory immune response linked to sepsis. Host guanylate binding proteins (GBPs) promote infect...
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| Veröffentlicht in: | mBio |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626967/ https://ncbi.nlm.nih.gov/pubmed/28974614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01188-17 |
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