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Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components

Gram-negative bacterial pathogens utilize virulence-associated secretion systems to inject, or translocate, effector proteins into host cells to manipulate cellular processes and promote bacterial replication. However, translocated bacterial products are sensed by nucleotide binding domain and leuci...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Zwack, Erin E., Feeley, Eric M., Burton, Amanda R., Hu, Baofeng, Yamamoto, Masahiro, Kanneganti, Thirumala-Devi, Bliska, James B., Coers, Jörn, Brodsky, Igor E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607426/
https://ncbi.nlm.nih.gov/pubmed/28784930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00778-16
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