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Role of the lysosomal membrane protein, CLN3, in the regulation of cathepsin D activity
Among Neuronal Ceroid Lipofuscinoses (NCLs), which are childhood fatal neurodegenerative disorders, the juvenile onset form (JNCL) is the most common. JNCL is caused by recessive mutations in the CLN3 gene. CLN3 encodes a lysosomal/endosomal transmembrane protein but its precise function is not comp...
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| Publicado no: | J Cell Biochem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5603378/ https://ncbi.nlm.nih.gov/pubmed/28390177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26039 |
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