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Abnormally increased surface expression of AMPA receptors in the cerebellum, cortex and striatum of Cln3(−/−) mice

Mutations in the CLN3 gene cause a fatal neurodegenerative disorder, juvenile CLN3 disease. Exploring the cause of the motor coordination deficit in the Cln3(−/−) mouse model of the disease we have previously found that attenuation of AMPA receptor activity in 1-month-old Cln3(−/−) mice significantl...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Kovács, Attila D., Hof, Caitlin, Pearce, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631631/
https://ncbi.nlm.nih.gov/pubmed/26375929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.09.012
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