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Antigen presenting cell abnormalities in the Cln3(−/−) mouse model of juvenile neuronal ceroid lipofuscinosis

Mutations of the CLN3 gene lead to juvenile neuronal ceroid lipofuscinosis (JNCL), an autosomal recessive lysosomal storage disorder that causes progressive neurodegeneration in children and adolescents. There is evidence of immune system involvement in pathology that has been only minimally investi...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Hersrud, Samantha L., Kovács, Attila D., Pearce, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899816/
https://ncbi.nlm.nih.gov/pubmed/27101989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.04.011
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