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Antigen presenting cell abnormalities in the Cln3(−/−) mouse model of juvenile neuronal ceroid lipofuscinosis

Mutations of the CLN3 gene lead to juvenile neuronal ceroid lipofuscinosis (JNCL), an autosomal recessive lysosomal storage disorder that causes progressive neurodegeneration in children and adolescents. There is evidence of immune system involvement in pathology that has been only minimally investi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta
Prif Awduron: Hersrud, Samantha L., Kovács, Attila D., Pearce, David A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899816/
https://ncbi.nlm.nih.gov/pubmed/27101989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.04.011
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