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Antigen presenting cell abnormalities in the Cln3(−/−) mouse model of juvenile neuronal ceroid lipofuscinosis

Mutations of the CLN3 gene lead to juvenile neuronal ceroid lipofuscinosis (JNCL), an autosomal recessive lysosomal storage disorder that causes progressive neurodegeneration in children and adolescents. There is evidence of immune system involvement in pathology that has been only minimally investi...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: Hersrud, Samantha L., Kovács, Attila D., Pearce, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899816/
https://ncbi.nlm.nih.gov/pubmed/27101989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.04.011
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