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Antigen presenting cell abnormalities in the Cln3(−/−) mouse model of juvenile neuronal ceroid lipofuscinosis
Mutations of the CLN3 gene lead to juvenile neuronal ceroid lipofuscinosis (JNCL), an autosomal recessive lysosomal storage disorder that causes progressive neurodegeneration in children and adolescents. There is evidence of immune system involvement in pathology that has been only minimally investi...
Shranjeno v:
| izdano v: | Biochim Biophys Acta |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899816/ https://ncbi.nlm.nih.gov/pubmed/27101989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.04.011 |
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