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Transcript and in silico analysis of CLN3 in juvenile neuronal ceroid lipofuscinosis and associated mouse models

Juvenile neuronal ceroid lipofuscinoses (JNCL), commonly known as Batten disease, is a progressive neurodegenerative disorder of childhood characterized by blindness, seizures, motor and cognitive decline, leading to death in early adulthood. Mutations within the CLN3 gene, which encodes a putative...

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Bibliografiske detaljer
Main Authors: Chan, Chun-Hung, Mitchison, Hannah M., Pearce, David A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722895/
https://ncbi.nlm.nih.gov/pubmed/18678598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn228
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