Osmotic Stress Changes the Expression and Subcellular Localization of the Batten Disease Protein CLN3

Juvenile CLN3 disease (formerly known as juvenile neuronal ceroid lipofuscinosis) is a fatal childhood neurodegenerative disorder caused by mutations in the CLN3 gene. CLN3 encodes a putative lysosomal transmembrane protein with unknown function. Previous cell culture studies using CLN3-overexpressi...

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Detalhes bibliográficos
Main Authors: Getty, Amanda, Kovács, Attila D., Lengyel-Nelson, Tímea, Cardillo, Andrew, Hof, Caitlin, Chan, Chun-Hung, Pearce, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688782/
https://ncbi.nlm.nih.gov/pubmed/23840424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066203
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