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The Role of N-Glycosylation in Folding, Trafficking, and Functionality of Lysosomal Protein CLN5
CLN5 is a soluble lysosomal protein with unknown function. Mutations in CLN5 lead to neuronal ceroid lipofuscinosis, a group of inherited neurodegenerative disorders that mainly affect children. CLN5 has eight potential N-glycosylation sites based on the Asn-X-Thr/Ser consensus sequence. Through sit...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769244/ https://ncbi.nlm.nih.gov/pubmed/24058541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074299 |
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