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The Role of Rhodopsin Glycosylation in Protein Folding, Trafficking, and Light-Sensitive Retinal Degeneration

Several mutations in the N terminus of the G-protein-coupled receptor rhodopsin disrupt NXS/T consensus sequences for N-linked glycosylation (located at N2 and N15) and cause sector retinitis pigmentosa in which the inferior retina preferentially degenerates. Here we examined the role of rhodopsin g...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tam, Beatrice M., Moritz, Orson L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665958/
https://ncbi.nlm.nih.gov/pubmed/19955366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4259-09.2009
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