Mislocalized Rhodopsin Does Not Require Activation to Cause Retinal Degeneration and Neurite Outgrowth in Xenopus laevis

Mutations in the C terminus of rhodopsin disrupt a rod outer segment localization signal, causing rhodopsin mislocalization and aggressive forms of retinitis pigmentosa (RP). Studies of cultured photoreceptors suggest that activated mislocalized rhodopsin can cause cell death via inappropriate G-pro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Tam, Beatrice M., Xie, Guifu, Oprian, Daniel D., Moritz, Orson L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2006
Materias:
Cellular/Molecular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674333/
https://ncbi.nlm.nih.gov/pubmed/16399688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3849-05.2006
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares