ロード中...

Pyruvate kinase M knockdown–induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival

Preferential expression of the low-activity (dimeric) M2 isoform of pyruvate kinase (PK) over its constitutively active splice variant M1 isoform is considered critical for aerobic glycolysis in cancer cells. However, our results reported here indicate co-expression of PKM1 and PKM2 and their possib...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Prakasam, Gopinath, Singh, Rajnish Kumar, Iqbal, Mohammad Askandar, Saini, Sunil Kumar, Tiku, Ashu Bhan, Bamezai, Rameshwar N. K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602412/
https://ncbi.nlm.nih.gov/pubmed/28778925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.791343
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!