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Resveratrol Inhibits Cancer Cell Metabolism by Down Regulating Pyruvate Kinase M2 via Inhibition of Mammalian Target of Rapamycin

Metabolism of cancer cells with pyruvate kinase M2 (PKM2) at its centre stage has assumed a prime significance in cancer research in recent times. Cancer cell metabolism, characterized by enhanced glucose uptake, production of lactate and anabolism is considered an ideal target for therapeutic inter...

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Autors principals: Iqbal, Mohd Askandar, Bamezai, Rameshwar N. K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344940/
https://ncbi.nlm.nih.gov/pubmed/22574221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036764
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