Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2

BACKGROUND: Insulin is tightly associated with cancer progression; however, mechanistic insights into such observations are poorly understood. Recent studies show that metabolic transformation is critical to cancer cell proliferation. Here, we attempt to understand the role of insulin in promotion o...

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Detalhes bibliográficos
Main Authors: Iqbal, Mohd Askandar, Siddiqui, Farid Ahmad, Gupta, Vibhor, Chattopadhyay, Shilpi, Gopinath, Prakasam, Kumar, Bhupender, Manvati, Siddharth, Chaman, Noor, Bamezai, Rameshwar NK
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710280/
https://ncbi.nlm.nih.gov/pubmed/23837608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-72
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