Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2

BACKGROUND: Insulin is tightly associated with cancer progression; however, mechanistic insights into such observations are poorly understood. Recent studies show that metabolic transformation is critical to cancer cell proliferation. Here, we attempt to understand the role of insulin in promotion o...

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Autori principali: Iqbal, Mohd Askandar, Siddiqui, Farid Ahmad, Gupta, Vibhor, Chattopadhyay, Shilpi, Gopinath, Prakasam, Kumar, Bhupender, Manvati, Siddharth, Chaman, Noor, Bamezai, Rameshwar NK
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710280/
https://ncbi.nlm.nih.gov/pubmed/23837608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-72
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