ERK2-Pyruvate Kinase Axis Permits Phorbol 12-Myristate 13-Acetate-induced Megakaryocyte Differentiation in K562 Cells

Metabolic changes that contribute to differentiation are not well understood. Overwhelming evidence shows the critical role of glycolytic enzyme pyruvate kinase (PK) in directing metabolism of proliferating cells. However, its role in metabolism of differentiating cells is unclear. Here we studied t...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Chaman, Noor, Iqbal, Mohammad Askandar, Siddiqui, Farid Ahmad, Gopinath, Prakasam, Bamezai, Rameshwar N. K.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2015
נושאים:
Metabolism
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583024/
https://ncbi.nlm.nih.gov/pubmed/26269597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657411
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