ERK2-Pyruvate Kinase Axis Permits Phorbol 12-Myristate 13-Acetate-induced Megakaryocyte Differentiation in K562 Cells

Metabolic changes that contribute to differentiation are not well understood. Overwhelming evidence shows the critical role of glycolytic enzyme pyruvate kinase (PK) in directing metabolism of proliferating cells. However, its role in metabolism of differentiating cells is unclear. Here we studied t...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chaman, Noor, Iqbal, Mohammad Askandar, Siddiqui, Farid Ahmad, Gopinath, Prakasam, Bamezai, Rameshwar N. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583024/
https://ncbi.nlm.nih.gov/pubmed/26269597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657411
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