ERK2-Pyruvate Kinase Axis Permits Phorbol 12-Myristate 13-Acetate-induced Megakaryocyte Differentiation in K562 Cells

Metabolic changes that contribute to differentiation are not well understood. Overwhelming evidence shows the critical role of glycolytic enzyme pyruvate kinase (PK) in directing metabolism of proliferating cells. However, its role in metabolism of differentiating cells is unclear. Here we studied t...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Chaman, Noor, Iqbal, Mohammad Askandar, Siddiqui, Farid Ahmad, Gopinath, Prakasam, Bamezai, Rameshwar N. K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583024/
https://ncbi.nlm.nih.gov/pubmed/26269597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657411
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items