Megakaryocytic differentiation in human chronic myelogenous leukemia K562 cells induced by ionizing radiation in combination with phorbol 12-myristate 13-acetate

Differentiation-induction therapy is an attractive approach in leukemia treatment. It has been suggested that the accumulation of intracellular reactive oxygen species (ROS) is involved in megakaryocytic differentiation induced by phorbol 12-myristate 13-acetate (PMA) in the K562 leukemia cell line....

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Detalhes bibliográficos
Main Authors: Hirose, Katsumi, Monzen, Satoru, Sato, Haruka, Sato, Mariko, Aoki, Masahiko, Hatayama, Yoshiomi, Kawaguchi, Hideo, Narita, Yuichiro, Takai, Yoshihiro, Kashiwakura, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650750/
https://ncbi.nlm.nih.gov/pubmed/23263730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrs125
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