Megakaryocytic differentiation in human chronic myelogenous leukemia K562 cells induced by ionizing radiation in combination with phorbol 12-myristate 13-acetate

Differentiation-induction therapy is an attractive approach in leukemia treatment. It has been suggested that the accumulation of intracellular reactive oxygen species (ROS) is involved in megakaryocytic differentiation induced by phorbol 12-myristate 13-acetate (PMA) in the K562 leukemia cell line....

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Detalles Bibliográficos
Autores principales: Hirose, Katsumi, Monzen, Satoru, Sato, Haruka, Sato, Mariko, Aoki, Masahiko, Hatayama, Yoshiomi, Kawaguchi, Hideo, Narita, Yuichiro, Takai, Yoshihiro, Kashiwakura, Ikuo
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650750/
https://ncbi.nlm.nih.gov/pubmed/23263730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrs125
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