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The 3-hydroxyacyl-CoA dehydratases HACD1 and HACD2 exhibit functional redundancy and are active in a wide range of fatty acid elongation pathways

Differences among fatty acids (FAs) in chain length and number of double bonds create lipid diversity. FA elongation proceeds via a four-step reaction cycle, in which the 3-hydroxyacyl-CoA dehydratases (HACDs) HACD1–4 catalyze the third step. However, the contribution of each HACD to 3-hydroxyacyl-C...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Sawai, Megumi, Uchida, Yukiko, Ohno, Yusuke, Miyamoto, Masatoshi, Nishioka, Chieko, Itohara, Shigeyoshi, Sassa, Takayuki, Kihara, Akio
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602410/
https://ncbi.nlm.nih.gov/pubmed/28784662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.803171
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