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ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

Very long-chain fatty acids (VLCFAs) exert a variety of cellular functions and are associated with numerous diseases. However, the precise pathway behind their elongation has remained elusive. Moreover, few regulatory mechanisms for VLCFAs synthesis have been identified. Elongases catalyze the first...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ohno, Yusuke, Suto, Shota, Yamanaka, Masao, Mizutani, Yukiko, Mitsutake, Susumu, Igarashi, Yasuyuki, Sassa, Takayuki, Kihara, Akio
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973002/
https://ncbi.nlm.nih.gov/pubmed/20937905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005572107
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