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ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

Very long-chain fatty acids (VLCFAs) exert a variety of cellular functions and are associated with numerous diseases. However, the precise pathway behind their elongation has remained elusive. Moreover, few regulatory mechanisms for VLCFAs synthesis have been identified. Elongases catalyze the first...

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Библиографические подробности
Главные авторы: Ohno, Yusuke, Suto, Shota, Yamanaka, Masao, Mizutani, Yukiko, Mitsutake, Susumu, Igarashi, Yasuyuki, Sassa, Takayuki, Kihara, Akio
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973002/
https://ncbi.nlm.nih.gov/pubmed/20937905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005572107
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