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ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

Very long-chain fatty acids (VLCFAs) exert a variety of cellular functions and are associated with numerous diseases. However, the precise pathway behind their elongation has remained elusive. Moreover, few regulatory mechanisms for VLCFAs synthesis have been identified. Elongases catalyze the first...

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Detalhes bibliográficos
Main Authors: Ohno, Yusuke, Suto, Shota, Yamanaka, Masao, Mizutani, Yukiko, Mitsutake, Susumu, Igarashi, Yasuyuki, Sassa, Takayuki, Kihara, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973002/
https://ncbi.nlm.nih.gov/pubmed/20937905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005572107
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