Diverse meibum lipids produced by Awat1 and Awat2 are important for stabilizing tear film and protecting the ocular surface

A lipid layer consisting of meibum lipids exists in the tear film and functions in preventing dry eye disease. Although the meibum lipids include diverse lipid classes, the synthesis pathway and role of each class remain largely unknown. Here, we created single and double knockout (KO and DKO, respe...

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Dettagli Bibliografici
Pubblicato in:iScience
Autori principali: Sawai, Megumi, Watanabe, Keisuke, Tanaka, Kana, Kinoshita, Wataru, Otsuka, Kento, Miyamoto, Masatoshi, Sassa, Takayuki, Kihara, Akio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169949/
https://ncbi.nlm.nih.gov/pubmed/34113821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102478
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