Diverse meibum lipids produced by Awat1 and Awat2 are important for stabilizing tear film and protecting the ocular surface

A lipid layer consisting of meibum lipids exists in the tear film and functions in preventing dry eye disease. Although the meibum lipids include diverse lipid classes, the synthesis pathway and role of each class remain largely unknown. Here, we created single and double knockout (KO and DKO, respe...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Sawai, Megumi, Watanabe, Keisuke, Tanaka, Kana, Kinoshita, Wataru, Otsuka, Kento, Miyamoto, Masatoshi, Sassa, Takayuki, Kihara, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169949/
https://ncbi.nlm.nih.gov/pubmed/34113821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102478
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