Impaired Epidermal Permeability Barrier in Mice Lacking Elovl1, the Gene Responsible for Very-Long-Chain Fatty Acid Production

The sphingolipid backbone ceramide (Cer) is a major component of lipid lamellae in the stratum corneum of epidermis and has a pivotal role in epidermal barrier formation. Unlike Cers in other tissues, Cers in epidermis contain extremely long fatty acids (FAs). Decreases in epidermal Cer levels, as w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sassa, Takayuki, Ohno, Yusuke, Suzuki, Shotaro, Nomura, Toshifumi, Nishioka, Chieko, Kashiwagi, Toshiki, Hirayama, Taisuke, Akiyama, Masashi, Taguchi, Ryo, Shimizu, Hiroshi, Itohara, Shigeyoshi, Kihara, Akio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2013
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700134/
https://ncbi.nlm.nih.gov/pubmed/23689133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00192-13
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