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Human ribonuclease H1 resolves R-loops and thereby enables progression of the DNA replication fork

Faithful DNA replication is essential for genome stability. To ensure accurate replication, numerous complex and redundant replication and repair mechanisms function in tandem with the core replication proteins to ensure DNA replication continues even when replication challenges are present that cou...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Parajuli, Shankar, Teasley, Daniel C., Murali, Bhavna, Jackson, Jessica, Vindigni, Alessandro, Stewart, Sheila A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602383/
https://ncbi.nlm.nih.gov/pubmed/28717002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787473
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