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FEN1 Ensures Telomere Stability by Facilitating Replication Fork Re-initiation

Telomeres are terminal repetitive DNA sequences whose stability requires the coordinated actions of telomere-binding proteins and the DNA replication and repair machinery. Recently, we demonstrated that the DNA replication and repair protein Flap endonuclease 1 (FEN1) is required for replication of...

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Detalhes bibliográficos
Main Authors: Saharia, Abhishek, Teasley, Daniel C., Duxin, Julien P., Dao, Benjamin, Chiappinelli, Katherine B., Stewart, Sheila A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930705/
https://ncbi.nlm.nih.gov/pubmed/20551483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.112276
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