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Coordinated Degradation of Replisome Components Ensures Genome Stability upon Replication Stress in the Absence of the Replication Fork Protection Complex

The stabilization of the replisome complex is essential in order to achieve highly processive DNA replication and preserve genomic integrity. Conversely, it would also be advantageous for the cell to abrogate replisome functions to prevent inappropriate replication when fork progression is adversely...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Roseaulin, Laura C., Noguchi, Chiaki, Martinez, Esteban, Ziegler, Melissa A., Toda, Takashi, Noguchi, Eishi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547854/
https://ncbi.nlm.nih.gov/pubmed/23349636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003213
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