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Coordinated Degradation of Replisome Components Ensures Genome Stability upon Replication Stress in the Absence of the Replication Fork Protection Complex

The stabilization of the replisome complex is essential in order to achieve highly processive DNA replication and preserve genomic integrity. Conversely, it would also be advantageous for the cell to abrogate replisome functions to prevent inappropriate replication when fork progression is adversely...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Roseaulin, Laura C., Noguchi, Chiaki, Martinez, Esteban, Ziegler, Melissa A., Toda, Takashi, Noguchi, Eishi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547854/
https://ncbi.nlm.nih.gov/pubmed/23349636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003213
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