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Human ribonuclease H1 resolves R-loops and thereby enables progression of the DNA replication fork

Faithful DNA replication is essential for genome stability. To ensure accurate replication, numerous complex and redundant replication and repair mechanisms function in tandem with the core replication proteins to ensure DNA replication continues even when replication challenges are present that cou...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Parajuli, Shankar, Teasley, Daniel C., Murali, Bhavna, Jackson, Jessica, Vindigni, Alessandro, Stewart, Sheila A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602383/
https://ncbi.nlm.nih.gov/pubmed/28717002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787473
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