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Reviving the guardian of the genome: small molecule activators of p53
The tumor suppressor p53 is one of the most important proteins for protection of genomic stability and cancer prevention. Cancers often inactivate it by either mutating its gene or disabling its function. Thus, activating p53 becomes an attractive approach for the development of molecule-based anti-...
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| Veröffentlicht in: | Pharmacol Ther |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601031/ https://ncbi.nlm.nih.gov/pubmed/28351719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.03.013 |
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