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Reviving the guardian of the genome: small molecule activators of p53

The tumor suppressor p53 is one of the most important proteins for protection of genomic stability and cancer prevention. Cancers often inactivate it by either mutating its gene or disabling its function. Thus, activating p53 becomes an attractive approach for the development of molecule-based anti-...

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Podrobná bibliografie
Vydáno v:Pharmacol Ther
Hlavní autoři: Nguyen, Daniel, Liao, Wenjuan, Zeng, Shelya X., Lu, Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601031/
https://ncbi.nlm.nih.gov/pubmed/28351719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.03.013
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