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p53 as guardian of the mitochondrial genome
Participating in the repair of nuclear DNA is one mechanism by which p53 suppresses tumorigenesis, but there is growing evidence that p53 also helps maintain the mitochondrial genome through its translocation into mitochondria and interactions with mtDNA repair proteins. Because of the susceptibilit...
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| Pubblicato in: | FEBS Lett |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833664/ https://ncbi.nlm.nih.gov/pubmed/26780878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12061 |
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