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p53 as guardian of the mitochondrial genome

Participating in the repair of nuclear DNA is one mechanism by which p53 suppresses tumorigenesis, but there is growing evidence that p53 also helps maintain the mitochondrial genome through its translocation into mitochondria and interactions with mtDNA repair proteins. Because of the susceptibilit...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Park, Ji-Hoon, Zhuang, Jie, Li, Jie, Hwang, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833664/
https://ncbi.nlm.nih.gov/pubmed/26780878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12061
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