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p53 as guardian of the mitochondrial genome

Participating in the repair of nuclear DNA is one mechanism by which p53 suppresses tumorigenesis, but there is growing evidence that p53 also helps maintain the mitochondrial genome through its translocation into mitochondria and interactions with mtDNA repair proteins. Because of the susceptibilit...

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Podrobná bibliografie
Vydáno v:FEBS Lett
Hlavní autoři: Park, Ji-Hoon, Zhuang, Jie, Li, Jie, Hwang, Paul M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833664/
https://ncbi.nlm.nih.gov/pubmed/26780878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12061
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