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Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity
p53, a critical tumor suppressor, regulates mitochondrial respiration, but how a nuclear protein can orchestrate the function of an organelle encoded by two separate genomes, both of which require p53 for their integrity, remains unclear. Here we report that the mammalian homolog of the yeast mitoch...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808663/ https://ncbi.nlm.nih.gov/pubmed/24101517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310908110 |
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