Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

Metabolic reprogramming toward aerobic glycolysis unavoidably favours methylglyoxal (MG) and advanced glycation end products (AGEs) formation in cancer cells. MG was initially considered a highly cytotoxic molecule with potential anti-cancer value. However, we have recently demonstrated that MG enha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nokin, Marie-Julie, Durieux, Florence, Bellier, Justine, Peulen, Olivier, Uchida, Koji, Spiegel, David A., Cochrane, James R., Hutton, Craig A., Castronovo, Vincent, Bellahcène, Akeila
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600983/
https://ncbi.nlm.nih.gov/pubmed/28916747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12119-7
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