Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer

Cancer cells generally rely on aerobic glycolysis as a major source of energy. Methylglyoxal (MG), a dicarbonyl compound that is produced as a side product during glycolysis, is highly reactive and induces the formation of advanced glycation end-products that are implicated in several pathologies in...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chiavarina, Barbara, Nokin, Marie-Julie, Bellier, Justine, Durieux, Florence, Bletard, Noëlla, Sherer, Félicie, Lovinfosse, Pierre, Peulen, Olivier, Verset, Laurine, Dehon, Romain, Demetter, Pieter, Turtoi, Andrei, Uchida, Koji, Goldman, Serge, Hustinx, Roland, Delvenne, Philippe, Castronovo, Vincent, Bellahcène, Akeila
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297842/
https://ncbi.nlm.nih.gov/pubmed/28117708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010213
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