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Regulation of cancer epigenomes with a histone-binding synthetic transcription factor

Chromatin proteins have expanded the mammalian synthetic biology toolbox by enabling control of active and silenced states at endogenous genes. Others have reported synthetic proteins that bind DNA and regulate genes by altering chromatin marks, such as histone modifications. Previously, we reported...

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Genom Med
Hauptverfasser: Nyer, David B., Daer, Rene M., Vargas, Daniel, Hom, Caroline, Haynes, Karmella A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600530/
https://ncbi.nlm.nih.gov/pubmed/28919981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-016-0002-3
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