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Design, Construction, and Validation of Histone-Binding Effectors in vitro and in Cells

Chromatin is a system of nuclear proteins and nucleic acids that plays a pivotal role in gene expression and cell behavior and is therefore the subject of intense study for cell development and cancer research. Biochemistry, crystallography, and reverse genetics have elucidated the macromolecular in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Tekel, Stefan J., Barrett, Cassandra, Vargas, Daniel, Haynes, Karmella A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370554/
https://ncbi.nlm.nih.gov/pubmed/29791133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00327
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