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Regulation of cancer epigenomes with a histone-binding synthetic transcription factor

Chromatin proteins have expanded the mammalian synthetic biology toolbox by enabling control of active and silenced states at endogenous genes. Others have reported synthetic proteins that bind DNA and regulate genes by altering chromatin marks, such as histone modifications. Previously, we reported...

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Detalles Bibliográficos
Publicado en:NPJ Genom Med
Main Authors: Nyer, David B., Daer, Rene M., Vargas, Daniel, Hom, Caroline, Haynes, Karmella A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600530/
https://ncbi.nlm.nih.gov/pubmed/28919981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-016-0002-3
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