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Regulation of cancer epigenomes with a histone-binding synthetic transcription factor

Chromatin proteins have expanded the mammalian synthetic biology toolbox by enabling control of active and silenced states at endogenous genes. Others have reported synthetic proteins that bind DNA and regulate genes by altering chromatin marks, such as histone modifications. Previously, we reported...

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Publicat a:NPJ Genom Med
Autors principals: Nyer, David B., Daer, Rene M., Vargas, Daniel, Hom, Caroline, Haynes, Karmella A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600530/
https://ncbi.nlm.nih.gov/pubmed/28919981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-016-0002-3
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