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Regulation of cancer epigenomes with a histone-binding synthetic transcription factor

Chromatin proteins have expanded the mammalian synthetic biology toolbox by enabling control of active and silenced states at endogenous genes. Others have reported synthetic proteins that bind DNA and regulate genes by altering chromatin marks, such as histone modifications. Previously, we reported...

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Bibliografiske detaljer
Udgivet i:NPJ Genom Med
Main Authors: Nyer, David B., Daer, Rene M., Vargas, Daniel, Hom, Caroline, Haynes, Karmella A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600530/
https://ncbi.nlm.nih.gov/pubmed/28919981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-016-0002-3
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