Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos

Upon fertilization, the genome of animal embryos remains transcriptionally inactive until the maternal-to-zygotic transition. At this time, the embryo takes control of its development and transcription begins. How the onset of zygotic transcription is regulated remains unclear. Here, we show that a...

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Udgivet i:eLife
Main Authors: Joseph, Shai R, Pálfy, Máté, Hilbert, Lennart, Kumar, Mukesh, Karschau, Jens, Zaburdaev, Vasily, Shevchenko, Andrej, Vastenhouw, Nadine L
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Developmental Biology and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451213/
https://ncbi.nlm.nih.gov/pubmed/28425915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23326
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