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Chromatin accessibility established by Pou5f3, Sox19b and Nanog primes genes for activity during zebrafish genome activation

In many organisms, early embryonic development is driven by maternally provided factors until the controlled onset of transcription during zygotic genome activation. The regulation of chromatin accessibility and its relationship to gene activity during this transition remain poorly understood. Here,...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Pálfy, Máté, Schulze, Gunnar, Valen, Eivind, Vastenhouw, Nadine L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986763/
https://ncbi.nlm.nih.gov/pubmed/31940339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008546
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