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Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition

Upon fertilization, maternal factors direct development and trigger zygotic genome activation (ZGA) at the maternal-to-zygotic transition (MZT). In zebrafish, ZGA is required for gastrulation and clearance of maternal mRNAs, which is in part regulated by the conserved microRNA miR-430. However, the...

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Detalhes bibliográficos
Main Authors: Lee, Miler T., Bonneau, Ashley R., Takacs, Carter M., Bazzini, Ariel A., DiVito, Kate R., Fleming, Elizabeth S., Giraldez, Antonio J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925760/
https://ncbi.nlm.nih.gov/pubmed/24056933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12632
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