Effect of the Anti‐C1s Humanized Antibody TNT009 and Its Parental Mouse Variant TNT003 on HLA Antibody–Induced Complement Activation—A Preclinical In Vitro Study

The classic pathway (CP) of complement is believed to significantly contribute to alloantibody‐mediated transplant injury, and targeted complement inhibition is currently considered to be a promising approach for preventing rejection. Here, we investigated the mode of action and efficacy of the huma...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Transplant
Hauptverfasser: Wahrmann, M., Mühlbacher, J., Marinova, L., Regele, H., Huttary, N., Eskandary, F., Cohen, G., Fischer, G. F., Parry, G. C., Gilbert, J. C., Panicker, S., Böhmig, G. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600102/
https://ncbi.nlm.nih.gov/pubmed/28251805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14256
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge