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Development of a Pediatric Physiologically Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data
Physiologically based pharmacokinetic (PBPK) modeling is a powerful tool used to characterize maturational changes in drug disposition to inform dosing across childhood; however, its use is limited in pediatric drug development. Access to pediatric pharmacokinetic data is a barrier to widespread app...
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| Publicado no: | Clin Pharmacokinet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5597447/ https://ncbi.nlm.nih.gov/pubmed/28290120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0525-5 |
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