Use of Opportunistic Clinical Data and a Population Pharmacokinetic Model to Support Dosing of Clindamycin for Premature Infants to Adolescents

Clindamycin is commonly prescribed to treat children with skin and skin structure infections (including those caused by community-acquired methicillin-resistant Staphylococcus aureus [CA-MRSA]), yet little is known about the pharmacokinetics (PK) across pediatric age groups. A population PK analysis...

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Main Authors: Gonzalez, Daniel, Melloni, Chiara, Yogev, Ram, Poindexter, Brenda B., Mendley, Susan R., Delmore, Paula, Sullivan, Janice E., Autmizguine, Julie, Lewandowski, Andrew, Harper, Barrie, Watt, Kevin M., Lewis, Kenneth C., Capparelli, Edmund V., Benjamin, Daniel K., Cohen-Wolkowiez, Michael
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169790/
https://ncbi.nlm.nih.gov/pubmed/24949994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2014.134
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