Characterization of the Population Pharmacokinetics of Ampicillin in Neonates Using an Opportunistic Study Design

Although ampicillin is the most commonly used drug in neonates, developmental pharmacokinetic (PK) data to guide dosing are lacking. Ampicillin is primarily renally eliminated, and developmental changes are expected to influence PK. We conducted an open-label, multicenter, opportunistic, prospective...

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Главные авторы: Tremoulet, Adriana, Le, Jennifer, Poindexter, Brenda, Sullivan, Janice E., Laughon, Matthew, Delmore, Paula, Salgado, Andrea, Ian-U Chong, Sandy, Melloni, Chiara, Gao, Jamie, Benjamin, Daniel K., Capparelli, Edmund V., Cohen-Wolkowiez, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068432/
https://ncbi.nlm.nih.gov/pubmed/24614374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02374-13
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