Characterization of the Population Pharmacokinetics of Ampicillin in Neonates Using an Opportunistic Study Design

Although ampicillin is the most commonly used drug in neonates, developmental pharmacokinetic (PK) data to guide dosing are lacking. Ampicillin is primarily renally eliminated, and developmental changes are expected to influence PK. We conducted an open-label, multicenter, opportunistic, prospective...

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Bibliografski detalji
Glavni autori: Tremoulet, Adriana, Le, Jennifer, Poindexter, Brenda, Sullivan, Janice E., Laughon, Matthew, Delmore, Paula, Salgado, Andrea, Ian-U Chong, Sandy, Melloni, Chiara, Gao, Jamie, Benjamin, Daniel K., Capparelli, Edmund V., Cohen-Wolkowiez, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068432/
https://ncbi.nlm.nih.gov/pubmed/24614374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02374-13
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