Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates

OBJECTIVE: To evaluate the relationship between ampicillin dosing, exposure, and seizures. STUDY DESIGN: Retrospective observational cohort study of electronic health record (EHR) data combined with pharmacokinetic model derived drug exposure predictions. EHR from 348 Pediatrix Medical Group neonata...

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Publicado no:J Pediatr
Main Authors: Hornik, Christoph P., Benjamin, Daniel K., Smith, P. Brian, Pencina, Michael J., Tremoulet, Adriana H., Capparelli, Edmund V, Ericson, Jessica E., Clark, Reese H., Cohen-Wolkowiez, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085855/
https://ncbi.nlm.nih.gov/pubmed/27522443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2016.07.011
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