Safety, Effectiveness, and Exposure-Response of Micafungin in Infants: Application of an Established Pharmacokinetics Model to Electronic Health Records

Micafungin is used off-label in the United States to treat invasive candidiasis in neonates. We used an established pharmacokinetic model to determine micafungin exposures for 46 courses in 39 hospitalized infants. In this small cohort of infants, micafungin exposure was not associated with laborato...

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Vydáno v:Pediatr Infect Dis J
Hlavní autoři: Rivera-Chaparro, Nazario D., Ericson, Jessica, Wu, Huali, Smith, P. Brian, Clark, Reese H., Benjamin, Daniel K., Cohen-Wolkowiez, Michael, Greenberg, Rachel G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163100/
https://ncbi.nlm.nih.gov/pubmed/29601453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000002045
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