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Pharmacokinetics and Safety of Micafungin in Infants Supported with Extracorporeal Membrane Oxygenation

BACKGROUND: Candida is a leading cause of infection in infants on extracorporeal membrane oxygenation (ECMO). Optimal micafungin dosing is unknown in this population because ECMO can alter drug pharmacokinetics (PK). METHODS: To characterize micafungin PK and safety in infants on ECMO, we conducted...

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Bibliografski detalji
Izdano u:Pediatr Infect Dis J
Glavni autori: Autmizguine, Julie, Hornik, Christoph P., Benjamin, Daniel K., Brouwer, Kim L. R., Hupp, Susan R., Cohen-Wolkowiez, Michael, Watt, Kevin M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071122/
https://ncbi.nlm.nih.gov/pubmed/27314826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000001268
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