Pharmacokinetics and Safety of Fluconazole in Young Infants Supported with Extracorporeal Membrane Oxygenation

BACKGROUND: Candida infections are a leading cause of infectious disease-related death in infants supported with extracorporeal membrane oxygenation (ECMO). The ECMO circuit can alter drug pharmacokinetics (PK), thus standard fluconazole dosing in children on ECMO may result in suboptimal drug expos...

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Main Authors: Watt, Kevin M., Benjamin, Daniel K., Cheifetz, Ira M., Moorthy, Ganesh, Wade, Kelly C., Smith, P. Brian, Brouwer, Kim L. R., Capparelli, Edmund V., Cohen-Wolkowiez, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444624/
https://ncbi.nlm.nih.gov/pubmed/22627870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0b013e31825d3091
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